Sm-a-actin

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Webb15 jan. 1992 · Addition of sequence between positions −151 and −257 (p257CAT) resulted in a 7-fold increase in chloramphenicol acetyltransferase activity over that of p151CAT in rat SMC, but not in chicken SMC. A genomic clone encoding the rat smooth muscle alpha-actin gene was isolated, and the 5'-flanking region was partially characterized. WebbSmooth muscle alpha-actin (αSMA) is the definitive marker for the activated cardiac fibroblast population known as the myofibroblast (Frangogiannis et al., 2000), but this …

Developmental changes in isoactin expression in rat aortic …

ACTA2 (commonly referred to as alpha-smooth muscle actin or α-SMA) is often used as a marker of myofibroblast formation. Studies have shown that ACTA2 is associated with TGF-β pathway that enhances contractile properties of hepatic stellate cells leading to liver fibrosis and cirrhosis . Visa mer ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a Visa mer • Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease". Folia Biologica. 42 (5): 227–30. doi:10.1007/BF02818986. PMID 8997639. S2CID Visa mer • GeneReviews/NIH/NCBI/UW entry on Thoracic Aortic Aneurysms and Aortic Dissections • Human ACTA2 genome location and ACTA2 gene details page in the Visa mer Webb1 mars 2003 · We hypothesized that ablation of smooth muscle α-actin (SM α-A), a contractile-cytoskeletal protein expressed in airway smooth muscle (ASM) cells, … csgo command give smoke

Characterization of an E-boxâ Dependent cis Element in the …

Webbimmunocytochemical analysis using antibodies specific for either SM a-actin (Skalli et al., 1986) or SM myosin heavy chain (Kawamoto and Adelstein, 1987). Microscopic evaluation of a number of fields failed to uncover SM a-actin- or SM myosin heavy chain-negative cells (data not shown). Additionally, the expression of SM a-actin in Webbalpha-Smooth muscle (alpha-sm) actin, an isoform typical of smooth muscle cells (SMC) and present in high amounts in vascular SMC, was demonstrated in the cytoplasm of … Webb11 apr. 2024 · ACT, Acceptance and Commitment Therapy, är en vidareutveckling av Kognitiv Beteendeterapi (KBT). Metoden går ut på att lära sig att acceptera smärtan och … csgo command give money

Sm-a-actin

Alpha Smooth Muscle Actin - an overview ScienceDirect Topics

WebbStress may directly activate transcription of the α-SM actin gene, since application of force across integrin binding sites has been shown to up-regulate α-SM actin promoter activity. 52 As mentioned above, mechanical force alone is not generally sufficient to induce myofibroblast differentiation and other factors are needed to act in concert, specifically … WebbThe antibody (also known as anti-α-Sm-1) is specific for the single isoform of α-smooth muscle actin. It reacts specifically with α-smooth muscle actin in immunoblotting …

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Webbin Sm-a-actin content with increasing age were due, in part, to an increase in Sm-a-actin synthesis. However, in SMCs from 90- and 180-day-old rats, the fractional content of Sm-a-actin exceeded its fractional synthesis at a time when total Sm-a-actin content was increas- ing. This suggests that Sm-a-actin turns over more slowly in mature animals. WebbSee all alpha smooth muscle Actin primary antibodies Description Mouse monoclonal [1A4] to alpha smooth muscle Actin Host species Mouse Tested applications Suitable …

Webbof SM a-actin expression involves a complex interaction of multiple positive and negative cis elements that act in a cell-type specific fashion.10–16 For example, a 547 bp SM a-actin promoter/CAT construct (p547CAT) had high activ-ity in cultured SMCs and in L6 skeletal myotubes, which are cell types that express SM a-actin in culture ... WebbAlpha smooth muscle actin antibody (ab5694) stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also …

Webb3 dec. 2007 · We identified 2 types of migrating cells with distinctive actin filament structures at the migrating front: type I (Figure (Figure5A), 5 A), cells with a large amount of F-actin stress fibers forming lamellum-like protrusions, and type II (Figure (Figure5A), 5 A), cells with a polarized morphology, a ruffling lamellipodium at the leading edge facing the … WebbSmooth Muscle Actin ( Figures 25-3, A, and 25-4, A) The smooth muscle actin (SMA) marker has a relatively long track record of use as a myoepithelial marker in breast …

WebbSM a-actin promoter is regulated through combinatorial interactions between different factors. Transforming growth factor-b induced activity of the 125-bp rat SM a-actin promoter is dependent on both an intact transforming growth factor-bcontrol element and intact CArG boxes.18 Addition-ally, the homeodomain factor MHox activates SM a-actin

WebbPulmonary lymphangioleiomyomatosis (LAM) is a rare genetic disease characterized by neoplastic growth of atypical smooth muscle-like LAM cells, destruction of lung parenchyma, obstruction of... csgo command give weaponWebbActin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells ( PubMed: 29581253 ). Actin exists in both … e4-wifiWebb22 okt. 2024 · Vascular smooth muscle cells (VSMCs) are indispensable components in foam cell formation in atherosclerosis. However, the mechanism behind foam cell formation of VSMCs has not been addressed. We ... e4 who dares winsWebbSMC-specific marker genes including SM a-actin, SM myosin heavy chain, SM22, h-caldesmon, calponin, and telokin. The CArGs within any given SMC-specific promoter are … csgo command godmode for one playerWebbThe Actin Alpha 2 (ACTA2) gene encoding smooth muscle aortic actin, was isolated and characterized. It was found that the ACTA2 gene contains at least 9 exons (7). Alpha smooth muscle actin appears to play an important functional role in myofibroblast contraction and migration. e4 wolf\\u0027s-headWebb21 mars 2024 · GeneCards Summary for ACTA2 Gene. ACTA2 (Actin Alpha 2, Smooth Muscle) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Aortic Aneurysm, Familial Thoracic 6 . Among its related pathways are Actin Nucleation by ARP-WASP Complex and Integrin Pathway . e500 motor mounts service costWebbOur Alpha-Smooth Muscle Actin monoclonal, polyclonal, recombinant monoclonal, cocktail and recombinant polyclonal antibodies are developed in Mouse, Rabbit and Goat. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to Alpha-Smooth Muscle Actin. e501 line too long 122 120 characters