WebDiagnosing ALS at Stanford. At Stanford, our experienced subspecialist doctors focus on recognizing the subtle, early signs of amyotrophic lateral sclerosis, which gives them an … Amyotrophic lateral sclerosis typically is diagnosed in middle age. There is a recognized male predilection 1. See more Both upper and lower motor neurons are affected, with decreased motor strength and wasting of the limb muscles, bulbar muscles, and diaphragm. There is a progressive loss of … See more Amyotrophic lateral sclerosis is a relentlessly progressive neurological disorder characterized by the death of upper motor neurons … See more Amyotrophic lateral sclerosis typically progresses to death in 2-6 years, usually from respiratory complications 5. Few therapies have been shown to extend survival, including riluzole, a glutamate antagonist 10,11. See more The earliest MR manifestation is hyperintensity on T2-weighted imaging in the corticospinal tracts, seen earliest in the internal capsule, … See more
Amyotrophic Lateral Sclerosis (ALS) Johns Hopkins Medicine
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Amyotrophic Lateral Sclerosis (ALS) and Other Motor Neuron Diseases
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