Tīmeklis2024. gada 28. jūl. · LAMP1/2 是溶酶体相关膜蛋白,相关抗体可用于标记溶酶体。 自噬信号通路的研究 自噬在细胞存活与死亡中是把双刃剑,既能促进细胞存活也会导致细胞凋亡,但其具体机制还有待研究,阐明自噬在细胞存活和死亡方面的作用机制,深入了解自噬信号通路有助于我们更好的理解自噬在维持细胞内稳态的作用,并了解其在肿瘤、 … Tīmeklis2024. gada 3. sept. · Despite widespread distribution of LAMP1 and the heterogeneous nature of LAMP1-labeled compartments, LAMP1 is routinely used as a lysosomal marker, and LAMP1-positive organelles are often referred to as lysosomes. In this study, we use immunoelectron microscopy and confocal imaging to provide quanti …
Lysosome associated membrane protein 1 (Lamp1) traffics
TīmeklisLAMP1 is a heavily glycosylated membrane protein which contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane-spanning segment and a short (11 amino acid) cytosolic tail. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Tīmeklislamp1 蛋白羧基末端暴露在细胞浆中,同时它含有一个将 lamp 蛋白靶向至溶酶体膜的酪氨酸分类基序 (4)。lamp1 和 lamp2 的蛋白序列有 37% 同源性。lamp1 和 lamp2 均 … jothe jotheyali written update
LAMP1 -丁香通 - biomart.cn
TīmeklisLAMP2蛋白;溶酶体关联膜蛋白2 (LAMP2)重组蛋白长期储存,建议添加载体蛋白(0.1%HSA或BSA),并储存在-20~ -80°C。. 避免多次冻融。. 影响蛋白原核表达 … TīmeklisMilana Fraiberg, Zvulun Elazar, in Progress in Molecular Biology and Translational Science, 2024. 3.4 LAMP2. The LAMP2 gene is located on the Xq24 chromosome. … Tīmeklis2024. gada 6. janv. · LAMP1 and LAMP2 are estimated to account for approximately 50% of lysosomal membrane proteins (Eskelinen 2006 ). LAMP1 possesses a large luminal ectodomain and transmembrane domain, followed by a short C-terminal cytoplasmic tail (Fukuda 1991; Eskelinen et al. 2003 ). jothe jotheyali today\u0027s written episode