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WebOct 18, 2024 · August 24, 2016. The human Cell Line Activation Test (h-CLAT) is a cell-based assay that identifies skin sensitizers by examining changes in the expression of cell surface markers (CD54 and CD86) implicated in dendritic cell activation, the third key event of the skin sensitization AOP. Following exposure of the THP-1 human monocyte cell line ... http://www.cosmedna.com/ charlie mackesy prints to buy
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Webh-CLAT Assay The h-CLAT is an in-vitro method on human dendritic-like cells (part of the immune system) expressing surface proteins needed to trigger an immune response. Increases in these proteins are detected using fluorescent-labelled antibodies and a flow cytometer. Sensitisers increase the number of these proteins on the exposed cells … WebJun 30, 2024 · In the h-CLAT and U-SENS assays, the changes of surface marker expression are measured by flow cytometry following cell staining with fluorochrome … WebA Korean Tradition Made in America. Shop Local, Shop Fresh. Shop Online. Highlights: Multiple Payment Options Available, Friendly Place. charlie mackesy mental health quotes