WebMar 24, 2024 · A multipart phase 1 study was conducted to determine the safety, tolerability, pharmacokinetics, and food effect of the novel oral oxazolidinone, MRX-I, in healthy adults, as well as the tolerability of longer-term exposure of both oral MRX-I and linezolid. Thirty subjects in part 1 received single … WebA total of 47 Chinese healthy adult male subjects re-ceived HC‐1119 soft capsule at a single oral dose of 40, 80, or 160mg followed on fasting or 160mg after high‐fat meal …
Phase I clinical trial of HC-1119 soft capsule in Chinese …
WebBEE of southern Chinese healthy adults and to develop a new equation for predicting BEE in southern Chinese healthy adults. Materials and methods Subjects A total of 165 recruited healthy Chinese adults aged 18–45 years with normal body weight (BMI, 18·5–24·0kg/m2) were involved in the present study. All the subjects were WebBackground: A formal single ascending and multiple dose pharmacokinetic (PK) trial of cannabidiol (CBD) oral solution was required to determine the safety and tolerability of CBD, the maximum tolerated dose, and to examine the effect of food on CBD PK parameters. Objective: This trial assessed the safety, tolerability and PK of CBD oral solution in … graphene elastic constants
Frontiers A Randomized Controlled Dose-Escalation Study of …
WebJan 21, 2024 · The limitations of this study include its small sample size, comprising only healthy Chinese adults; therefore, the safety data may not have enough statistical power. Another limitation is that two subjects withdrew during the trial; however, we fully considered this issue before commencement of the trial and included an additional 10% … WebA total of 47 Chinese healthy adult male subjects received HC-1119 soft capsule at a single oral dose of 40, 80, or 160 mg followed on fasting or 160 mg after high-fat meal … WebStatistical analysis. All statistical analyses were performed by IBM SPSS Statistics 23.0. All statistical tests were two-tailed and the significance criterion was set at P<0.05.Demographic and clinical characteristics between overweight/obesity and control groups were examined by independent-samples t-tests.Differences in age and sex between overweight/obese … chips internet