Web品系描述. 将CreERT2表达框定点敲入小鼠内源Alb基因ATG位置，建立Tamoxifen诱导的Alb-Cre工具鼠。. 该品系已去除Neo筛选基因。. 该小鼠是研究肝脏基因功能与疾病的重要小鼠品系。. 应用领域 ：肝脏特异. WebNeurofibromatosis Type 1 (NF1) is an autosomal dominant genetic disorder that results in a variety of characteristic manifestations. Prior studies have shown reduced muscle size and global skeletal muscle weakness in children with NF1. This associated weakness can lead to significant challenges impa …
资源库Cre工具鼠列表及链接 - 常用工具鼠简介 - 技术支持 - 国家遗 …
WebCDX2 is a homeobox gene that encodes a transcription protein factor that guides development of intestinal epithelial cells from the region of the duodenum to the … Web008875 B6.129P2- Lgr5 tm1(cre/ERT2)Cle /J Heterozygous mice harbor an Lgr5-EGFP-IRES-creERT2 "knock-in" allele that both abolishes Lgr5 gene function and expresses EGFP and CreERT2 fusion protein. When these mice mice are bred with mice containing a loxP -flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will … peroxide bleaches hair
022390 - B6.Cg-Tg(CDX2-Cre/ERT2)752Erf/J
Web008085 - UBC-Cre-ERT2 Strain Details. Overview. MOUSE PHENOME DATABASE. Web捐赠者报道了 Lgr5-EGFP-IRES-CreERT2 转基因在小肠和结肠中多样化的表达（在小肠发育早期表达的基因经常出现的情况）。. 这种多样化的表达有利于进行谱系追踪和小肠干细胞分离，但对于更多的定量研究如 Lgr5-Cre 驱动的基因敲除策略可能存在局限性。. Cre-ERT2 ... Web这种鼠在正常情况下由于3×stop的存在并不能表达红色荧光，当与Cre鼠或TAM激活的CreERT2鼠交配后，产生的后代由于Cre重组酶切割loxp位点之间的序列将3×stop切除，TdTomato得到表达，就可以在Cre或CreERT2表 … peroxide cleaning grout